Evaluation of Biological Parameters of Diabetic Patients Treated with Medicinal Plants: Case of the City of N'Djamena
Elise Dagosse,
Memti Mberdoum Nguinambaye,
Nadjioroum Ngam Asra,
Brahim Boy Otchom
Issue:
Volume 8, Issue 4, December 2022
Pages:
66-73
Received:
8 October 2022
Accepted:
27 October 2022
Published:
10 November 2022
DOI:
10.11648/j.jdmp.20220804.11
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Abstract: Diabetes is a metabolic disorder related to the secretion and / or absorption of insulin by the body, it is characterized mainly by a high level of glucose in the blood beyond 1.10 g / l. The objective of this study is to contribute to the development of medicinal plants that can help in the management of diabetes mellitus. The data collected during this study were done through a direct interview on the basis of an ethnobotanical survey form. The data of the study were analyzed on Excel and then SPSS version 22.0. Blood samples of 30 diabetic patients of both sexes subjected to plant-based treatments were collected. The different assays were performed at time 0 and 8 weeks after the first sample. The average age of the patients was 44.13 years with extremes of 18 and 70 years and a male predominance at 56%. Twenty-three medicinal plants were identified, 6 of which were used in the composition of three recipes for diabetic patients. The recipe composed of Leptadenia hastata + Guiera senegalensis had a 100% favorable effect on the carbohydrate parameters. On the other hand, the recipe composed of Boscia senegalensis+Anogeissus leiocarpus+Guiera senegalensis and the one composed of Prosopis africana+ Indigofera astragalana + Guiera senegalensis had a 57.1% and 55.6% favorable effect respectively on the carbohydrate parameters by restoring the glycemic balance All these 3 recipes had no toxic effect on the liver and kidneys: transaminases and creatine remained stable. A phytochemical and pharmacological study on animals with these plants will allow the development of phytomedicines against diabetes.
Abstract: Diabetes is a metabolic disorder related to the secretion and / or absorption of insulin by the body, it is characterized mainly by a high level of glucose in the blood beyond 1.10 g / l. The objective of this study is to contribute to the development of medicinal plants that can help in the management of diabetes mellitus. The data collected durin...
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